Epidemiology of Pulmonary Tuberculosis in Diabetes Mellitus Patients

Authors

  • Siti Ananda Hardita Syahputri RS Bina Sehat Jember
  • Diana Chusna Mufida Universitas Jember
  • Candra Bumi Universitas Jember

DOI:

https://doi.org/10.26630/jk.v14i2.3963

Keywords:

DM type 2, Pulmonary TB, Risk factors.

Abstract

Pulmonary Tuberculosis (pulmonary TB) and Type 2 Diabetes Mellitus (DMT2) are the leading causes of death worldwide. The prevalence of T2DM has increased worldwide as an aging result, urbanization, changes in diet, and reduced physical activity patterns, which have increased obesity. Pulmonary TB and T2DM often occur together and complicate each other during treatment. Pulmonary TB infection-DMT2 appears based on a low immunity state. When the body has low immunity, the reactivation of Mycobacterium tuberculosis bacteria can occur more easily. However, several factors can influence it. This study uses a case-control design. The researcher made observations on the subjects by comparing the case group and the control group. This study had 74 respondents in the case group and 74 respondents in the control group using quota sampling. This study has the results that the factors that influence the incidence of pulmonary TB-DMT2 are smoking behavior 0.000<α, history of contact with pulmonary TB patients 0.009<α, adherence to taking OAD 0.011<α, duration of DM 0.028<α, and gender 0.029<α. Factors that do not affect the incidence of pulmonary TB-DMT2 are nutritional status 0.077>α, family history of DM 0.5>α, income 0.677>α, blood sugar level 0.826>α, occupation 0.876>α, age 0.877>α, and alcohol consumption 0.998>α. (α=0.05). The factor that most influences the risk of pulmonary TB-DMT2 is smoking behavior with a wald value of 13.391. This research provides information regarding the problem of pulmonary TB-DMT2 in Jember. To increase public awareness of the risk for Pulmonary TB-DMT2.

Author Biography

Siti Ananda Hardita Syahputri, RS Bina Sehat Jember

Perawat IGD

References

Arania, R., Triwahyuni, T., Esfandiari, F., & Nugraha, F. R. (2021). Hubungan antara usia, jenis kelamin, dan tingkat pendidikan dengan kejadian diabetes mellitus di Klinik Mardi Waluyo Lampung Tengah. Jurnal Medika Malahayati, 5(3), 146-153. https://doi.org/10.33024/jmm.v5i3.4200

Elycia, D., & Halim, S. (2020). Karakteristik pasien diabetes melitus tipe 2 dengan tuberkulosis paru di Rumah Sakit Sumber Waras tahun 2016-2018. Tarumanagara Medical Journal, 2(1), 20-26. https://doi.org/10.24912/tmj.v2i2.7832

Fauzia, D. F., Basyar, M., & Manaf, A. (2016). Insidensi tuberkulosis paru pada pasien diabetes melitus tipe 2 di ruang rawat inap penyakit dalam RSUP Dr. M. Djamil Padang. Jurnal Kesehatan Andalas, 5(2). https://doi.org/10.25077/jka.v5i2.520

Hapsari, P. N. F., & Isfandiari, M. A. (2017). Hubungan sosioekonomi dan gizi dengan risiko tuberkulosis pada penderita DM tipe 2. Jurnal Berkala Epidemiologi, 5(2), 185-194.

Harahap, F. Z. (2021). Hubungan Diabetes Melitus Dengan Kejadian Tuberkulosis (Studi Case Control Di RSUD Kotapinang). [Skripsi]. Medan: Universitas Islam Negeri Sumatera Utara. http://repository.uinsu.ac.id/13344/.

Hidayah, H., Amal, S., & Rosmalinda, A. N. (2021). Insidensi TB Paru pada Pasien DM tipe 2 di Rumah Sakit Karya Husada Cikampek. Pharma Xplore: Jurnal Sains dan Ilmu Farmasi, 6(1), 23-31. https://journal.ubpkarawang.ac.id/index.php/Farmasi/article/view/1446

International Diabetes Federation. (2017). IDF Diabetes Atlas Eighth Edition 2017. International Diabetes Federation.

Irawan, B. (2020). Tuberkulosis (TB) Paru pada Penderita Diabetes Mellitus Tipe 2 (DMT2) (Studi Kasus Kontrol di Wilayah Kerja Puskesmas Patrang Kabupaten Jember). [Skripsi]. Jember: Fakultas Kesehatan Masyarakat, Universitas Jember.

Klein, S. L., Marriott, I., & Fish, E. N. (2015). Sex-based differences in immune function and responses to vaccination. Transactions of the Royal Society of Tropical Medicine and Hygiene, 109(1), 9-15. https://doi.org/10.1093/trstmh/tru167

Komariah. (2020). Relationship between Age, Gender, and Body Mass Index with Fasting Blood Sugar Levels in Type 2 Diabetes Mellitus Patients at the Proklamasi Outpatient Primary Clinic, Depok, West Java. Kusuma Husada health journal 6(2). https://jurnal.ukh.ac.id/index.php/JK/article/view/412

Lumbanraja, N. (2017). Karakteristik Penderita Diabetes Melitus Tipe II dengan Tuberkulosis Paru di RSUD DR. Pirngadi Medan Tahun 2016. [Skripsi]. Medan: Fakultas Kesehatan Masyarakat, Universitas Sumatera Utara.

Lusiani, E. (2019). Faktor Risiko Terjadinya Manifestasi TB Paru Pada Penderita DM Tipe 2 Dengan Tes Mantoux Positif. Jurnal Keperawatan Muhammadiyah, 4(2). https://journal.um-surabaya.ac.id/index.php/JKM/article/view/2527

Musdalifah. (2020). The Relationship between Gender and Economic Level with the Incidence of Diabetes Mellitus in the Working Area of the Palaran Health Center, Samarinda City, in 2019. Borneo Student Research 1(2) 2020

Novita, E., Ismah, Z. dan Pariyana, P. (2018). Angka kejadian diabetes melitus pada pasien tuberkulosis. Jurnal Kedokteran dan Kesehatan Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya.5(1), pp. 20–25.

Oktafiyana, F., Nurhayati, N., & Almurhan, A. (2017). Hubungan lingkungan kerja penderita tb paru terhadap kejadian penyakit tb paru. Jurnal Ilmiah Keperawatan Sai Betik, 12(1), 52-57. https://ejurnal.poltekkes-tjk.ac.id/index.php/JKEP/article/view/344

Restrepo BI. (2016). Diabetes and Tuberculosis. Microbiol Spectr, 4(6)

Sa'adah, N., Prasetyowati, I. and Bumi, C. (2022). Relationship of Contact History with Pulmonary Tuberculosis Patients on the Incidence of TB-DM in the Work Area of the Kalisat Health Center, Indonesian Public Health Media, 21(3), pp. 184–189.

Savitri, Adinda Ratih, Muliani, Yuliana. (2021). Characteristics of pulmonary tuberculosis patients with diabetes mellitus in Badung Regency in 2017-2018. Udayana Medical Journal, 10 (1) 2021

Tandang, F., Amat, S.L.A., Pakan, D.P., (2018). Hubungan Kebiasaan Merokok Pada Perokok Aktif Dan Pasif Dengan Kejadian Tuberkulosis Paru Di Puskesmas Sikumana Kota Kupang. Cendana Medical Journal, 15(3), 382–390.

Utomo, R. (2016). Correlation between Type 2 Diabetes Mellitus Status and Extensive Lesion Pulmonary Tuberculosis Status. Diponegoro Medical Journal, 5 (4)

vom Steeg, L. G., & Klein, S. L. (2016). SeXX matters in infectious disease pathogenesis. PLoS pathogens, 12(2), e1005374. https://doi.org/10.1371/journal.ppat.1005374

Workneh, M. H., Bjune, G. A., & Yimer, S. A. (2017). Prevalence and associated factors of tuberculosis and diabetes mellitus comorbidity: a systematic review. PloS one, 12(4), e0175925. https://doi.org/10.1371/journal.pone.0175925

Yonge, S.A., Otieno, M.F., Sharma, R.R., Omedo, R.C.A. (2016). Risk Factors in Transmission of Tuberculosis Infection in Mombasa, Kenya: An Epidemiological Descriptive Study. International Journal of Tropical Disease & Health, 13(4): 1-10

Yosephine, M. K., Hardy, F. R., Wenny, D. M., Nurrizka, R. H., & Pulungan, R. M. (2021). Faktor yang Memengaruhi Kejadian Tuberkulosis Paru pada Penderita Diabetes Mellitus di Rumah Sakit X. Jurnal Kesehatan, 12(3), 344-351. http://dx.doi.org/10.26630/jk.v12i3.2542

Zheng, C., Hu, M., & Gao, F. (2017). Diabetes and pulmonary tuberculosis: a global overview with special focus on the situation in Asian countries with high TB-DM burden. Global health action, 10(1), 1264702. https://doi.org/10.1080/16549716.2016.1264702

Downloads

Published

05-10-2023