Epidemiology of Pulmonary Tuberculosis in Diabetes Mellitus Patients
DOI:
https://doi.org/10.26630/jk.v14i2.3963Keywords:
DM type 2, Pulmonary TB, Risk factors.Abstract
Pulmonary Tuberculosis (pulmonary TB) and Type 2 Diabetes Mellitus (DMT2) are the leading causes of death worldwide. The prevalence of T2DM has increased worldwide as an aging result, urbanization, changes in diet, and reduced physical activity patterns, which have increased obesity. Pulmonary TB and T2DM often occur together and complicate each other during treatment. Pulmonary TB infection-DMT2 appears based on a low immunity state. When the body has low immunity, the reactivation of Mycobacterium tuberculosis bacteria can occur more easily. However, several factors can influence it. This study uses a case-control design. The researcher made observations on the subjects by comparing the case group and the control group. This study had 74 respondents in the case group and 74 respondents in the control group using quota sampling. This study has the results that the factors that influence the incidence of pulmonary TB-DMT2 are smoking behavior 0.000<α, history of contact with pulmonary TB patients 0.009<α, adherence to taking OAD 0.011<α, duration of DM 0.028<α, and gender 0.029<α. Factors that do not affect the incidence of pulmonary TB-DMT2 are nutritional status 0.077>α, family history of DM 0.5>α, income 0.677>α, blood sugar level 0.826>α, occupation 0.876>α, age 0.877>α, and alcohol consumption 0.998>α. (α=0.05). The factor that most influences the risk of pulmonary TB-DMT2 is smoking behavior with a wald value of 13.391. This research provides information regarding the problem of pulmonary TB-DMT2 in Jember. To increase public awareness of the risk for Pulmonary TB-DMT2.References
Arania, R., Triwahyuni, T., Esfandiari, F., & Nugraha, F. R. (2021). Hubungan antara usia, jenis kelamin, dan tingkat pendidikan dengan kejadian diabetes mellitus di Klinik Mardi Waluyo Lampung Tengah. Jurnal Medika Malahayati, 5(3), 146-153. https://doi.org/10.33024/jmm.v5i3.4200
Elycia, D., & Halim, S. (2020). Karakteristik pasien diabetes melitus tipe 2 dengan tuberkulosis paru di Rumah Sakit Sumber Waras tahun 2016-2018. Tarumanagara Medical Journal, 2(1), 20-26. https://doi.org/10.24912/tmj.v2i2.7832
Fauzia, D. F., Basyar, M., & Manaf, A. (2016). Insidensi tuberkulosis paru pada pasien diabetes melitus tipe 2 di ruang rawat inap penyakit dalam RSUP Dr. M. Djamil Padang. Jurnal Kesehatan Andalas, 5(2). https://doi.org/10.25077/jka.v5i2.520
Hapsari, P. N. F., & Isfandiari, M. A. (2017). Hubungan sosioekonomi dan gizi dengan risiko tuberkulosis pada penderita DM tipe 2. Jurnal Berkala Epidemiologi, 5(2), 185-194.
Harahap, F. Z. (2021). Hubungan Diabetes Melitus Dengan Kejadian Tuberkulosis (Studi Case Control Di RSUD Kotapinang). [Skripsi]. Medan: Universitas Islam Negeri Sumatera Utara. http://repository.uinsu.ac.id/13344/.
Hidayah, H., Amal, S., & Rosmalinda, A. N. (2021). Insidensi TB Paru pada Pasien DM tipe 2 di Rumah Sakit Karya Husada Cikampek. Pharma Xplore: Jurnal Sains dan Ilmu Farmasi, 6(1), 23-31. https://journal.ubpkarawang.ac.id/index.php/Farmasi/article/view/1446
International Diabetes Federation. (2017). IDF Diabetes Atlas Eighth Edition 2017. International Diabetes Federation.
Irawan, B. (2020). Tuberkulosis (TB) Paru pada Penderita Diabetes Mellitus Tipe 2 (DMT2) (Studi Kasus Kontrol di Wilayah Kerja Puskesmas Patrang Kabupaten Jember). [Skripsi]. Jember: Fakultas Kesehatan Masyarakat, Universitas Jember.
Klein, S. L., Marriott, I., & Fish, E. N. (2015). Sex-based differences in immune function and responses to vaccination. Transactions of the Royal Society of Tropical Medicine and Hygiene, 109(1), 9-15. https://doi.org/10.1093/trstmh/tru167
Komariah. (2020). Relationship between Age, Gender, and Body Mass Index with Fasting Blood Sugar Levels in Type 2 Diabetes Mellitus Patients at the Proklamasi Outpatient Primary Clinic, Depok, West Java. Kusuma Husada health journal 6(2). https://jurnal.ukh.ac.id/index.php/JK/article/view/412
Lumbanraja, N. (2017). Karakteristik Penderita Diabetes Melitus Tipe II dengan Tuberkulosis Paru di RSUD DR. Pirngadi Medan Tahun 2016. [Skripsi]. Medan: Fakultas Kesehatan Masyarakat, Universitas Sumatera Utara.
Lusiani, E. (2019). Faktor Risiko Terjadinya Manifestasi TB Paru Pada Penderita DM Tipe 2 Dengan Tes Mantoux Positif. Jurnal Keperawatan Muhammadiyah, 4(2). https://journal.um-surabaya.ac.id/index.php/JKM/article/view/2527
Musdalifah. (2020). The Relationship between Gender and Economic Level with the Incidence of Diabetes Mellitus in the Working Area of the Palaran Health Center, Samarinda City, in 2019. Borneo Student Research 1(2) 2020
Novita, E., Ismah, Z. dan Pariyana, P. (2018). Angka kejadian diabetes melitus pada pasien tuberkulosis. Jurnal Kedokteran dan Kesehatan Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya.5(1), pp. 20–25.
Oktafiyana, F., Nurhayati, N., & Almurhan, A. (2017). Hubungan lingkungan kerja penderita tb paru terhadap kejadian penyakit tb paru. Jurnal Ilmiah Keperawatan Sai Betik, 12(1), 52-57. https://ejurnal.poltekkes-tjk.ac.id/index.php/JKEP/article/view/344
Restrepo BI. (2016). Diabetes and Tuberculosis. Microbiol Spectr, 4(6)
Sa'adah, N., Prasetyowati, I. and Bumi, C. (2022). Relationship of Contact History with Pulmonary Tuberculosis Patients on the Incidence of TB-DM in the Work Area of the Kalisat Health Center, Indonesian Public Health Media, 21(3), pp. 184–189.
Savitri, Adinda Ratih, Muliani, Yuliana. (2021). Characteristics of pulmonary tuberculosis patients with diabetes mellitus in Badung Regency in 2017-2018. Udayana Medical Journal, 10 (1) 2021
Tandang, F., Amat, S.L.A., Pakan, D.P., (2018). Hubungan Kebiasaan Merokok Pada Perokok Aktif Dan Pasif Dengan Kejadian Tuberkulosis Paru Di Puskesmas Sikumana Kota Kupang. Cendana Medical Journal, 15(3), 382–390.
Utomo, R. (2016). Correlation between Type 2 Diabetes Mellitus Status and Extensive Lesion Pulmonary Tuberculosis Status. Diponegoro Medical Journal, 5 (4)
vom Steeg, L. G., & Klein, S. L. (2016). SeXX matters in infectious disease pathogenesis. PLoS pathogens, 12(2), e1005374. https://doi.org/10.1371/journal.ppat.1005374
Workneh, M. H., Bjune, G. A., & Yimer, S. A. (2017). Prevalence and associated factors of tuberculosis and diabetes mellitus comorbidity: a systematic review. PloS one, 12(4), e0175925. https://doi.org/10.1371/journal.pone.0175925
Yonge, S.A., Otieno, M.F., Sharma, R.R., Omedo, R.C.A. (2016). Risk Factors in Transmission of Tuberculosis Infection in Mombasa, Kenya: An Epidemiological Descriptive Study. International Journal of Tropical Disease & Health, 13(4): 1-10
Yosephine, M. K., Hardy, F. R., Wenny, D. M., Nurrizka, R. H., & Pulungan, R. M. (2021). Faktor yang Memengaruhi Kejadian Tuberkulosis Paru pada Penderita Diabetes Mellitus di Rumah Sakit X. Jurnal Kesehatan, 12(3), 344-351. http://dx.doi.org/10.26630/jk.v12i3.2542
Zheng, C., Hu, M., & Gao, F. (2017). Diabetes and pulmonary tuberculosis: a global overview with special focus on the situation in Asian countries with high TB-DM burden. Global health action, 10(1), 1264702. https://doi.org/10.1080/16549716.2016.1264702
Downloads
Additional Files
Published
Issue
Section
License
Authors who publish in this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
