Uji Daya Hambat Perasan Air Kunyit (Curcuma domestica Val.) sebagai Antibakteri terhadap Pertumbuhan Bakteri Escherichia coli

Authors

  • Nur Lulu Fitriyani Universitas Pekalongan
  • Rezeki Widayati Fakultas Ilmu Kesehatan, Universitas Pekalongan
  • Aris Santjaka Jurusan Kesehatan Lingkungan, Politeknik Kesehatan Kemenkes Semarang
  • Ristiawati Ristiawati Fakultas Ilmu Kesehatan, Universitas Pekalongan
  • Jaya Maulana Fakultas Ilmu Kesehatan, Universitas Pekalongan

DOI:

https://doi.org/10.26630/jk.v13i3.3257

Keywords:

Antibacteri, Inhibitory effect, Tumeric water.

Abstract

Diarrhea cases in Indonesia were 270/1000 population or 7,265,013 cases occurred at all ages with a mortality rate (CFR) of 4.76% in 2018. Treatment of diarrhea can be done by giving antibiotics such as Cefotaxime, Ciprofloxacin, Gentamicin, Ampicillin, Metronidazole, Co-trioxide, Ceftriaxone, and Erythromycin. However, inappropriate use of antibiotics can lead to bacterial resistance. Turmeric is a medicinal plant that contains curcumin and essential oils that can inhibit the growth of bacteria. There are 24 essential oils in turmeric, which are dominated by turmerone (35.16%), ar-turmerone (25.20%), curlon (18.21%), and ar-curcumin (3.74%). Turmeric water obtained through juice has the potential as an antibacterial agent. This study is a pure experiment using a post-test-only control group design by examining the effect of turmeric juice (Curcuma domestica Val.) as an antibacterial of Escherichia coli bacteria. The results showed the ability of turmeric juice to inhibit the growth of Escherichia coli bacteria. The concentration of turmeric juice was able to produce an inhibition zone at concentrations ranging from 40% at 14 mm and the highest concentration at 100% at 24 mm. The results of the One Way Anova test showed that the results were not significant because the p-value>0.05 (p-value=0.351). This means that the average diameter of the inhibition at the concentration of turmeric juice 40%, 55%, 70%, 85%, and 100% did not have a significant difference. Turmeric juice has effectiveness in inhibiting the growth of E.coli bacteria.

References

Adhitama, W., Puspitasari, I., & Laksanawati, I. S. (2021). Evaluasi Luaran Klinis Terapi Antibiotika pada Pasien Anak Rawat Inap Dengan Infeksi Saluran Kemih di RSUP Dr. Sardjito Yogyakarta. Majalah Farmaseutik, 17(2), 166. https://doi.org/10.22146/farmaseutik.v17i2.48803

Arirahmayanti, I. G. A. E., Artini, I. G. A., & Ernawati, D. K. (2019). Perbandingan Aktivitas Antibakteri Ekstrak Etanol Kunyit (Curcuma longa) dan Bawang Putih (Allium sativum) terhadap Escherichia coli ATCC 8739 Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Udayana Bagian Farmakologi Fakultas Kedokt. Jurnal Medika Udayana, 8(11), 1–5. https://ojs.unud.ac.id/index.php/eum/article/download/55068/32670

Asyikin, A. (2017). Studi Identifikasi Drug Releated Problem’s (Drps) Pada Pasien Diare Di Perawatan Anak Rsud Pangkep Sulawesi Selatan. Media Farmasi Poltekes Makasar, 8(2). https://doi.org/https://doi.org/10.32382/mf.v13i2.787

Cobra, L. S., & Amini, H. W. (2019). Skirining Fitokimia Ekstrak Sokhletasi Rimpang Kunyit (Curcuma longa) dengan Pelarut Etanol 96%. Jurnal Ilmiah Kesehatan Karya Putra Bangsa, 1(1), 12-17. https://www.journal.stikes-kartrasa.ac.id/index.php/jurnalkartrasa/article/view/4

Fiana, F. M., Kiromah, N. Z. W., & Purwanti, E. (2020). Aktivitas Antibakteri Ekstrak Etanol Daun Sukun (Artocarpus altilis) Terhadap Bakteri Staphylococcus aureus Dan Escherichia coli. Pharmacon: Jurnal Farmasi Indonesia, spesial issue, 10–20. https://doi.org/10.23917/pharmacon.v0i0.10108

Kasta, G. (2020). Antimicrobial Activity of Ethanol Extract of Rhizome Turmeric (Curcuma Longa L.) For Growth of Escherichia coli, Staphylococcus aureus and Candida albicans. Asian Journal of Pharmaceutical Research and Development, 8(6), 77–80. https://doi.org/10.22270/ajprd.v8i3.712

Kebede, B. H., Forsido, S. F., Tola, Y. B., & Astatkie, T. (2021). Free radical scavenging capacity, antibacterial activity and essential oil composition of turmeric (Curcuma domestica) varieties grown in Ethiopia. Heliyon, 7(2). https://doi.org/10.1016/J.HELIYON.2021.E06239

Kementerian Kesehatan RI. (2019). Profil Kesehatan Indonesia Tahun 2019. Jakarta. https://kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-Indonesia-2019.pdf

Khumairoh, I. S. (2018). Uji Aktivitas Antifungi Lengkuas Merah (Alpinia Purpurata), Kunyit (Curcuma longa), dan Jahe (Zingiber officinale) Terhadap Candida albicans. [Skripsi]. Surabaya: Universitas Islam negeri Sunan Ampel. http://digilib.uinsby.ac.id/26028/1/Ika Sayyidatul Khumairoh_H71214017.pdf

Momoh, J. O., Manuwa, A. A., & Bankole, Y. O. (2022). Phytochemical Screening, Atomic Absorption Spectroscopy, GC-MS and Antibacterial Activities of Turmeric (Curcuma longa L.) Rhizome Extracts. Journal of Advances in Microbiology, 22(9), 116–131. https://doi.org/10.9734/JAMB/2022/v22i930498

Ningsih, A. W., Hanifa, I., & Hisbiyah, A. (2020). Pengaruh Perbedaan Metode Ekstraksi Rimpang Kunyit (Curcuma domestica) Terhadap Rendemen dan Skrining Fitokimia. Journal of Pharmaceutical Care Anwar Medika, 2(2), 49–57. http://repository.stikesrsanwarmedika.ac.id/id/eprint/249/2/Jurnal Publikasi.pdf

Nisa, E. F. (2016). Gambaran Sensitivitas Berbagai Antibiotik Dan Profil Plasmid Escherichia Coli Isolat Air Sumur Gali Desa Ngemplak Kabupaten Pati. [Skripsi]. Semarang: Universitas Muhammadiyah Semarang. http://repository.unimus.ac.id/121/

Oktavia, M., & Permana, D. D. (2022). Sensitivitas Antibiotik Paten dan Generik Terhadap Beberapa Bakteri Penyebab Diare. Yarsi Journal of Pharmacology, 3(2), 92–99. https://academicjournal.yarsi.ac.id/index.php/yjp/article/view/2655

Ola, N. F. (2017). Uji Aktivitas Antibakteri Ekstrak Aquous RIMPANG KUNYIT{Curcuma domesdca Val.)Terhadap Isolat Bakteri Escherichia Coli Dari Pasien Diare Di Rumah Sakit Muhammadiyah Palembang. [Skripsi]. Palembang: Fakultas Kedokteran, Universitas Muhammadiyah Palembang. http://repository.um-palembang.ac.id/id/eprint/523/1/SKRIPSI361-1704263370.pdf

Patil, V., Surwase, S., Belure, A., Suryawanshi, A., & Mane, D. (2019). Phytochemical Analysis and Antibacterial Evaluation of Curcuma. Ijpsr, 10(April), 2000–2003. https://doi.org/10.13040/IJPSR.0975-8232.10(4).2000-03

Pranata, S. T. (2014). Herbal Toga; (Tanaman Obat Keluarga) Gaya Hidup Sehat Alami dengan Apotek Hidup. Perpustakaan Umum Kota Solok. Aksara Sukses.

Pratiwi, A. M. (2016). Daya Bunuh Air Perasan Rimpang Kunyit (Curcuma domestica Val) terhadap Kematian Larva Aedes aegypti [Skripsi]. Semarang: Universitas Negeri Semarang. http://lib.unnes.ac.id/26222/1/6411412103.pdf

Ramdhani, P., Erly, & Asterina. (2017). Hambat Ekstrak Etanol Rimpang Kunyit (Curcuma domestica V.) terhadap Pertumbuhan Bakteri Staphylococcus aureus Secara In Vitro | Ramadhani | Jurnal Kesehatan Andalas. Jurnal Kesehatan Andalas, 6(3), 590–595. http://jurnal.fk.unand.ac.id/index.php/jka/article/view/743/599

Sumampouw, O. J. (2018). Uji Sensitivitas Antibiotik Terhadap Bakteri Escherichia Coli Penyebab Diare Balita Di Kota Manado (The Sensitivity Test of Antibiotics to Escherichia coli was Caused The Diarhhea... Sosio-economic factors of Underfive children Diarrhea in Coastal Area Manado. Journal of Current Pharmaceutical Sciences, 2(1), 104–110. https://www.researchgate.net/publication/328601359

Ulfah, M. U. (2020). Aktivitas Antibakteri Ekstrak Aseton Rimpang Kunyit (Curcuma domestica) terhadap Bakteri Staphylococcus aureus dan Escherichia coli. Jurnal FARMAKU (Farmasi Muhammadiyah Kuningan), 5(1), 25–31. https://stikes-muhammadiyahku.ac.id/ojs.stikes-muhammadiyahku.ac.id/index.php/jurnalfarmaku/article/view/82

Verma, R. K., Kumari, P., Maurya, R. K., Kumar, V., Verma, R. B., & Singh, R. K. (2018). Medicinal properties of turmeric (Curcuma longa L.): A review. Int. J. Chem. Stud, 6(4), 1354-1357. https://www.chemijournal.com/archives/?year=2018&vol=6&issue=4&ArticleId=3186&si=false

Downloads

Published

13-12-2022

Issue

Vol. 13 No. 3 (2022): Jurnal Kesehatan

Section

Articles

License

Authors who publish in this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  2. Authors can enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.