Aplikasi Diet Vegan dalam Menurunkan Kadar Purin pada Lansia Pasca Menopause

Authors

  • Leo Yosdimyati Romli STIKES Insan Cendekia Medika Jombang
  • Harnanik Nawangsari STIKES Insan Cendekia Medika Jombang

DOI:

https://doi.org/10.26630/jkm.v14i2.2953

Keywords:

Diet, Gout, Menopause, Purin, Vegan.

Abstract

Background: Menopausal women often have higher purine levels in their blood due to hormonal factors. Inability to manage nutrition or non-adherence to a low-purine diet also contributes to increased purine levels after menopause. Purpose: The purpose of this study was to determine the application of a vegan diet in reducing purine levels in the postmenopausal elderly. Methods: The research was conducted using a pre-experimental one-group pre-post-test design. The research sample was taken by purposive sampling technique with respondents taken based on the inclusion criteria set by the researcher so that 27 respondents were selected. The data collection method was carried out by measuring purine levels using a purine level examination tool/stick, which was carried out before and after the intervention by the researcher. Data analysis was performed using the Wilcoxon test statistical test. Result: The results showed that the application of a vegan diet had an effect in reducing purine levels in the postmenopausal elderly with a p-value = 0.006, almost half of the respondents had high purine levels before being given a vegan diet with a percentage of 40.7%, and after the application of the vegan diet showed a change/increase in normal conditions with a percentage of 85.2%. Conclusion: The application of the vegan diet method in the postmenopausal elderly has proven to be effective in reducing/controlling purine levels so that the vegan diet method routinely meets the nutritional needs of the postmenopausal elderly is recommended.

Abstrak. Latar Belakang: Wanita menopause sering memiliki kadar purin yang lebih tinggi dalam darah mereka karena faktor hormonal. Ketidakmampuan untuk mengelola nutrisi atau ketidakpatuhan dengan diet rendah purin juga berkontribusi pada peningkatan kadar purin setelah menopause. Tujuan: Tujuan penelitian ini membuktikan aplikasi diet vegan dalam menurunkan kadar purin pada lansia pasca menopause. Metode: Penelitian dilakukan dengan menggunakan desain penelitian pra eksperiment one group pre post test design. Sampel penelitian diambil dengan teknik purposive sampling dengan responden diambil berdasarkan kriteria inklusi yang telah ditetapkan oleh peneliti, sehingga terpilih sebanyak 27 responden. Metode pengumpulan data dilakukan dengan pengukuran kadar purin menggunakan alat/stick pemeriksaan kadar purin yang dilakukan sebelum dan sesudah pemberian intervensi oleh peneliti. Analisis data dilakukan dengan menggunakan uji statistik wilcoxon test. Hasil: Hasil penelitian menunjukkan bahwa aplikasi diet vegan memiliki pengaruh dalam menurunkan kadar purin pada lansia pasca menopause dengan nilai p-value = 0,006, hampir separuh dari responden memiliki kadar purin pada kondisi yang tinggi sebelum diberikan diet vegan dengan presentase 40,7%, dan pasca aplikasi diet vegan menunjukkan perubahan/peningkatan pada kondisi yang normal dengan presentase 85,2%. Simpulan: Aplikasi metode diet vegan pada lansia pasca menopause terbukti efektif untuk menurunkan/mengontrol kadar purin, sehingga penerapan metode diet vegan secara rutin dalam pemenuhan kebutuhan nutrisi lansia pasca menopause direkomendasikan.

References

Afnuhazi, R. (2019). Faktor-Faktor Yang Berhubungan Dengan Kejadian Gout Pada Lansia. Human Care Journal, 4(1), 34. https://doi.org/10.32883/hcj.v4i1.242

Aihemaitijiang, S., Zhang, Y., Zhang, L., Yang, J., Ye, C., Halimulati, M., Zhang, W., & Zhang, Z. (2020). The Association between Purine-Rich Food Intake and Hyperuricemia: A Cross-Sectional Study in Chinese Adult Residents. Nutrients, 12(12), 3835. https://doi.org/10.3390/nu12123835

Asamane, E. A., Greig, C. A., Aunger, J. A., & Thompson, J. L. (2019). Perceptions and factors influencing eating behaviours and physical function in community-dwelling ethnically diverse older adults: A longitudinal qualitative study. Nutrients, 11(6), 1–24. https://doi.org/10.3390/nu11061224

Benn, C. L., Dua, P., Gurrell, R., Loudon, P., Pike, A., Ian Storer, R., & Vangjeli, C. (2018). Physiology of hyperuricemia and urate-lowering treatments. Frontiers in Medicine, 5(MAY), 1–28. https://doi.org/10.3389/fmed.2018.00160

Chiu, T. H. T., Liu, C. H., Chang, C. C., Lin, M. N., & Lin, C. L. (2020). Vegetarian diet and risk of gout in two separate prospective cohort studies. Clinical Nutrition, 39(3), 837–844. https://doi.org/10.1016/J.CLNU.2019.03.016

Dall, G. V., & Britt, K. L. (2020). Estrogen Effects on the Mammary Gland in Early and Late Life and Breast Cancer Risk. 7(May 2017), 1–10. https://doi.org/10.3389/fonc.2017.00110

El Khoudary, S. R., Aggarwal, B., Beckie, T. M., Hodis, H. N., Johnson, A. E., Langer, R. D., Limacher, M. C., Manson, J. E., Stefanick, M. L., & Allison, M. A. (2020). Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement from the American Heart Association. Circulation, 142(25), e506–e532. https://doi.org/10.1161/CIR.0000000000000912

George, C., & Minter, D. A. (2021). Hyperuricemia. In StatPearls. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK459218/

Hu, J., Xu, W., Yang, H., & Mu, L. (2021). Uric acid participating in female reproductive disorders: a review. Reproductive Biology and Endocrinology : RB&E, 19(1), 65. https://doi.org/10.1186/S12958-021-00748-7

Jakše, B., Jakše, B., Pajek, M., & Pajek, J. (2019). Uric Acid and Plant-Based Nutrition. Nutrients, 11(8). https://doi.org/10.3390/NU11081736

Keenan, R. T., Krasnokutsky, S., & Pillinger, M. H. (2017). Etiology and Pathogenesis of Hyperuricemia and Gout. Kelley and Firestein’s Textbook of Rheumatology, 1597-1619.e6. https://doi.org/10.1016/B978-0-323-31696-5.00094-2

Kussoy, V. F. M., Kundre, R., & Wowiling, F. (2019). Kebiasaan Makan Makanan Tinggi Purin Dengan Kadar Asam Urat Di Puskesmas. Jurnal Keperawatan, 7(2), 1–7. https://doi.org/10.35790/jkp.v7i2.27476

Li, L., Zhang, Y., & Zeng, C. (2020). Update on the epidemiology, genetics, and therapeutic options of hyperuricemia. American Journal of Translational Research, 12(7), 3167–3181. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407685/

Li, R., Yu, K., & Li, C. (2018). Dietary factors and risk of gout and hyperuricemia: A meta-analysis and systematic review. Asia Pacific Journal of Clinical Nutrition, 27(6), 1344–1356. https://doi.org/10.6133/apjcn.201811_27(6).0022

Lidiawati, M., & Fadhil, I. (2019). Hubungan Pola Makan Dengan Kadar Asam Urat Pada Wanita Postmenopause Diposyandu Lansia Wilayah Kerja Puskesmas Krueng Barona Jaya Aceh Besar. Semdi Unaya, 306–315. Retrieved from http://jurnal.abulyatama.ac.id/index.php/semdiunaya/article/view/461

Pangestu et al, R. (2019). Status Menopause Dapat Meningkatkan Kadar Asam Urat. Journals of Ners Community, 10(November), 140–156. https://doi.org/https://doi.org/10.5281/j%20ners%20community.v10i2.867

Patroni, R. (2018). Perbedaan Kadar Asam Urat Pada Wanita Perimenopause Dan Menopause. Jurnal Media Kesehatan, 10(2), 159–162. https://doi.org/10.33088/jmk.v10i2.338

Peacock, K., & Ketvertis, K. M. (2021). Menopause. StatPearls. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK507826/

Ragab, G., Elshahaly, M., & Bardin, T. (2017). Gout : An old disease in new perspective – A review. Journal of Advanced Research, 8(5), 495–511. https://doi.org/10.1016/j.jare.2017.04.008

Saputro, O. H., & Amalia, H. (2018). Hubungan Antara Status Gizi Dengan Kadar Asam Urat Darah Pada Lansia. Penelitian Dan Karya Ilmiah, 3(2), 45. https://doi.org/10.25105/pdk.v3i2.2987

Sebastiani, G., Barbero, A. H., Borrás-Novell, C., Casanova, M. A., Aldecoa-Bilbao, V., Andreu-Fernández, V., Tutusaus, M. P., Martínez, S. F., Roig, M. D. G., & García-Algar, O. (2019). The Effects of Vegetarian and Vegan Diet during Pregnancy on the Health of Mothers and Offspring. Nutrients, 11(3). https://doi.org/10.3390/NU11030557

Vedder, D., Walrabenstein, W., Heslinga, M., Vries, R. de, Nurmohamed, M., Schaardenburg, D. van, & Gerritsen, M. (2019). Dietary Interventions for Gout and Effect on Cardiovascular Risk Factors: A Systematic Review. Nutrients, 11(12). https://doi.org/10.3390/NU11122955

Wibowo, D. A., & Nadhilah, S. (2020). Hubungan Pengetahuan Tentang Menopause Dengan Kecemasan Pada Wanita Premenopause Di Kelurahan Kertasari Kecamatan Ciamis Kabupaten Ciamis. Jurnal Keperawatan Galuh, 2(1), 1–8. https://doi.org/http://dx.doi.org/10.25157/jkg.v2i1.3736

Yuni, I., Mulyantina, M., & Juliani, J. (2018). Hubungan Citra Tubuh Dengan Kecemasan Pada Wanita yang Mengalami Menopause di Gampong Ateuk Pahlawan Kecamatan Baiturrahman Banda Aceh. Jurnal Aceh Medika, 2(1), 125–131. Retrieved from http://jurnal.abulyatama.ac.id/index.php/acehmedika/article/view/169

Zeng, Y., Pu, X., Yang, J., Du, J., Yang, X., Li, X., Li, L., Zhou, Y., & Yang, T. (2018). Preventive and therapeutic role of functional ingredients of barley grass for chronic diseases in human beings. Oxidative Medicine and Cellular Longevity, 2018. https://doi.org/10.1155/2018/3232080

Downloads

Published

2021-12-31