Dampak COVID-19 pada Kesehatan Ibu Hamil : Literature Review

Authors

  • Chahya Kharin Herbawani UPN Veteran Jakarta

DOI:

https://doi.org/10.26630/jkm.v13i2.2253

Keywords:

Covid-19, Public health, Maternal, Pregnancy

Abstract

Background: Coronavirus is a large family of viruses that can cause illness from mild to severe symptoms. COVID-19 attacks of all ages including vulnerable groups such as pregnant women. Numbers of previous studies on the coronavirus, (SARS-CoV and MERS-CoV), stated that pregnant women have a higher risk of severe disease, morbidity and mortality compared to the general population. Purpose: Currently there is limited research on COVID-19 in relation to pregnancy and childbirth. This study aims to determine the risks and impacts of COVID-19 on pregnancy and childbirth.

Methods: This study used a systematic review method. Sources of literature data were obtained from Google Scholar, PubMed, and Proquest taken from 2019-2020. Results: The results of the study based on 13 articles with a total of 363 pregnant women showed that there was no difference in the signs and symptoms experienced by pregnant women with Covid-19 infection when compared to the general population. Until now, a number of studies have been conducted to determine the vertical transmission of COVID-19 from mother to fetus. A number of samples such as umbilical cord blood, amniotic fluid, neonatal throat swab, breast milk, and vaginal secretions were taken for examination and showed negative results. Conclusion: Maternal-fetal transmission of COVID-19 was undetected in the majority of reported cases. But, pregnancy monitoring with COVID-19 and steps to prevent neonatal infection is still needed. Mothers who are infected are at a higher risk of having severe respiratory complications.

Latar Belakang: Coronavirus merupakan keluarga besar virus yang dapat mengakibatkan penyakit dari gejala ringan sampai gejala berat. COVID-19 menyerang semua usia termasuk kelompok rentan, salah satunya ibu hamil. Sejumlah penelitian mengenai coronavirus sebelumnya, (SARS-CoV dan MERS-CoV), menyebutkan bahwa ibu hamil berisiko lebih tinggi terhadap penyakit parah, morbiditas, dan mortalitas dibandingkan dengan populasi umum. Tujuan: Saat ini masih sedikit penelitian mengenai COVID-19 hubungannya dengan kehamilan dan persalinan. Penelitian ini bertujuan untuk mengetahui risiko dan dampak dari COVID-19 terhadap kehamilan dan persalinan.

Metode: Penelitian ini menggunakan metode systematic review. Sumber data literatur diperoleh dari Google Scholar, PubMed, dan Proquest yang diambil dari tahun 2019-2020. Hasil: Hasil penelitian berdasarkan 13 artikel dengan total 363 ibu hamil menunjukkan bahwa tidak terdapat perbedaan tanda dan gejala yang dialami oleh ibu hamil dengan infeksi covid-19 bila dibandingkan dengan populasi umum. Hingga saat ini sejumlah studi telah dilakukan untuk mengetahui adanya transmisi vertikal COVID-19 dari ibu ke janin. Sejumlah sampel seperti darah tali pusat, cairan ketuban, swab tenggorokan neonatal, ASI, dan sekresi vagina telah diambil untuk dilakukan pemeriksaan dan menunjukkan hasil negatif. Simpulan: Penularan ibu-janin dari COVID-19 tidak terdeteksi pada sebagian besar kasus yang dilaporkan.  Namun pemantauan kehamilan yang cermat dengan COVID-19 dan langkah-langkah untuk mencegah infeksi neonatal tetap diperlukan. Ibu yang terinfeksi berisiko lebih tinggi memiliki komplikasi pernapasan berat.

Author Biography

Chahya Kharin Herbawani, UPN Veteran Jakarta

Program Studi Kesehatan Masyarakat UPN Veteran Jakarta

References

Antoun, L., Taweel, N. El, Ahmed, I., Patni, S., & Honest, H. (2020). Maternal COVID-19 infection , clinical characteristics , pregnancy , and neonatal outcome : A prospective cohort study. European Journal of Obstetrics and Gynecology, (2019), 8–11. https://doi.org/10.1016/j.ejogrb.2020.07.008

Atmojo, J. T., Akbar, P. S., & Kuntari, S. (2020). Definisi dan Jalur Penularan Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS-Cov-2 ). Jurnal Pendidikan Kesehatan, 9(1), 57–64.

Breslin, N., Baptiste, C., Gyamfi-Bannerman, C., Miller, R., Martinez, R., Bernstein, K., … Goffman, D. (2020). Coronavirus Disease 2019 Infection Among Asymptomatic and Symptomatic Pregnant Women: Two Weeks of Confirmed Presentations to An Affiliated Pair of New York City Hospitals. American Journal of Obstetrics & Gynecology MFM, 2(2), 1–7. https://doi.org/https://doi.org/10.1016/j.ajogmf.2020.100118

Breslin, N., Baptiste, C., Miller, R., Fuchs, K., & Goffman, D. (2020). Coronavirus disease 2019 in pregnancy: early lessons, 2019(May), 1–3. https://doi.org/10.1016/j.ajogmf.2020.100111

Chen, H., Guo, J., Wang, C., Luo, F., Yu, X., Zhang, W., … Yang, H. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women : a retrospective review of medical records. The Lancet, 395(10226), 809–815. https://doi.org/10.1016/S0140-6736(20)30360-3

Chen, Yan, Peng, H., Wang, L., Zhao, Y., Zeng, L., Gao, H., & Liu, Y. (2020). Infants Born to Mothers With a New Coronavirus (COVID-19). Frontiers in Pediatrics, 8(104), 1–5. https://doi.org/10.3389/fped.2020.00104

Chen, Yanfen, & Bai, J. (2020). Maternal and infant outcomes of full-term pregnancy combined with COVID-2019 in Wuhan, China: retrospective case series. Archives of Gynecology and Obstetrics, 1–7. https://doi.org/10.1007/s00404-020-05573-8

Elshafeey, F., Magdi, R., Hindi, N., Elshebiny, M., Nasser, M., Kamel, M., … Maher, M. (2020). A systematic Scoping Review of COVID-19 During Pregnancy and Childbirth, (May), 47–52. https://doi.org/10.1002/ijgo.13182

Gugus Tugas Percepatan Penanganan COVID. (2020). Informasi terbaru seputar penanganan COVID-19 di Indonesia. Retrieved from covid19.go.id

Hantoushzadeh, S., Shamshirsaz, A. A., Aleyasin, A., Seferovic, M. D., Aski, S. K., Arian, S. E., … Aagaard, K. (2020). Maternal death due to COVID-19. The American Journal of Obstetrics & Gynecology, 223(1), 109.e1-109.e16. https://doi.org/10.1016/j.ajog.2020.04.030

Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., … Cao, B. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet, 395(10223), 497–506. https://doi.org/10.1016/S0140-6736(20)30183-5

Karimi-Zarchi, M., Neamatzadeh, H., & Alireza, S. (2020). Vertical Transmission of Coronavirus Disease 19 ( COVID-19 ) from Infected Pregnant Mothers to Neonates : A Review. Fetal and Pediatric Pathology, 0(0), 1–5. https://doi.org/10.1080/15513815.2020.1747120

Khan, S., Peng, L., Siddique, R., Nabi, G., Nawsherwan, Xue, M., … Han, G. (2020). Impact of COVID-19 infection on pregnancy outcomes and the risk of maternal-to-neonatal intrapartum transmission of COVID-19 during natural birth. Infection Control & Hospital Epidemiology, 41(6), 748–750. https://doi.org/10.1017/ice.2020.84

Liu, D., Li, L., Zheng, D., Wang, J., Yang, L., & Zheng, C. (2020). Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis. American Journal of Roentgenology, 215(July), 1–6.

London, V., Jr, R. M., Atallah, F., Cepeda, C., Mccalla, S., Fisher, N., … Minkoff, H. (2020). The Relationship between Status at Presentation and Outcomes among Pregnant Women with COVID-19. American Journal of Perinatology, 37(10), 991–994. https://doi.org/10.1055/s-0040-1712164

Perkumpulan Obstetri dan Ginekologi Indonesia. (2020). Rekomendasi Penanganan Infeksi Virus Corona (Covid-19) Pada Maternal (Hamil, Bersalin Dan Nifas). Penanganan Infeksi Virus Corona Pada Maternal, 1(3), 9–11. Retrieved from https://pogi.or.id/publish/rekomendasi-penanganan-infeksi-virus-corona-covid-19-pada-maternal/

Pradana, A. A., Casman, & Nur’aini. (2020). Pengaruh Kebijakan Social Distancing Pada Wabah Covid-19 Terhadap Kelompok Rentan di Indonesia. Jurnal Kebijakan Kesehatan Indonesia, 09(2), 61–67.

Schwartz, D. A., & Graham, A. L. (2020). Potential Maternal and Infant Outcomes from Coronavirus 2019-nCoV (SARS-CoV-2) Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections. Viruses, 12(194), 1–16.

Sentilhes, L., Marcillac, F. De, Jouffrieau, C., Kuhn, P., Thuet, V., Hansmann, Y., … Deruelle, P. (2020). Coronavirus disease 2019 in pregnancy was associated with maternal morbidity and preterm birth. American Journal of Obstetrics & Gynecology MFM, 1–15. https://doi.org/10.1016/j.ajog.2020.06.022

WHO. (2020a). Situation Report-49 SITUATION IN NUMBERS total and new cases in last 24 hours.

WHO. (2020b). WHO Coronavirus Disease (COVID-19) Dashboard. Retrieved from https://covid19.who.int/?gclid=Cj0KCQjwjer4BRCZARIsABK4QeU0FrvzuF-h2mKCUvm87kFcy4bsmwMagbdvlsUJqY8Db9tAEbuo1REaAgpBEALw_wcB

Yan, J., Guo, J., Fan, C., Juan, J., Yu, X., Li, J., … Yang, H. (2020). Coronavirus disease 2019 in pregnant women: a report based on 116 cases. The American Journal of Obstetrics & Gynecology, 223(1), 111.e1-111.e14. https://doi.org/10.1016/j.ajog.2020.04.014

Yu, N., Li, W., Kang, Q., Xiong, Z., Wang, S., Lin, X., … Chen, S. (2020). Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan , China : a retrospective , single-centre , descriptive study. The Lancet Infectious Diseases, 20(5), 559–564. https://doi.org/10.1016/S1473-3099(20)30176-6

Zaigham, M., & Andersson, O. (2020). Maternal and perinatal outcomes with COVID-19 : A systematic review of 108 pregnancies, 1–7. https://doi.org/10.1111/aogs.13867

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Published

2021-05-11